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Program Director

Mitchell S. Cairo, MD 
Mitchell_Cairo@nymc.edu
914.594.2150

Associate Director

Jessica Hochberg, MD 
Jessica_Hochberg@cwpw.org
914.493.7997 

Download Brochure

HCM Brochure


 

Blood and Marrow Transplant


Blood and Marrow Transplant

Our Blood and Marrow Transplantation (BMT) Program performs both autologous and allogeneic stem cell transplants. Our highly skilled, multidisciplinary team is dedicated to the therapeutic use of bone marrow, peripheral blood, cord blood and cellular therapy in the treatment of malignant, non-malignant, and serious blood-related disorders. Providers utilize personalized medicine, treating each patient as an individual. The BMT Program has the ability to provide full intensity, reduced intensity and reduced toxicity chemotherapy as part of the conditioning (aka chemotherapy) regimens prior to transplant.

Types of Bone Marrow Transplants

Autologous Bone Marrow Transplant

For some diseases, the patient’s own stem cells are removed and given back after receiving chemotherapy and/or radiation. This is known as an autologous transplant.

Allogeneic Bone Marrow Transplant

For other diseases, patients cannot use their own stem cells for a transplant so they must use a donor, either related or unrelated. This is known as an allogenic transplant.

Related Donor Transplant

A related donor transplant utilizes a relative. Siblings are more likely to be a match for transplant, but parents can also be used as donors.

Matched Unrelated Donor Transplant

If you do not have a family member that is a match, an international search for a matched unrelated donor is performed through the National Marrow Donor Program (NMDP). For more information about finding a donor (or becoming one), visit www.bethematch.org.

Haploidentical Stem Transplants

Haploidentical Stem Cell Transplants (half-matched family donor transplants) are sometimes used to broaden the donor pool and make it easier to find a donor.

Cord Blood Transplants

Some people choose to donate their infant’s umbilical cord blood at the time of birth. This cord blood is frozen and can be used for stem cell transplants.

Diseases We Treat

An asterisk indicates our practice is involved in a clinical trial associated with the disease. View our current clinical trials here.

Malignant Diseases

  • Acute Lymphoblastic Leukemia*
  • Acute Myeloid Leukemia*
  • Chronic Myeloid Leukemia*
  • Juvenile Myelomonocytic Leukemia*
  • Multiple Myeloma*
  • Non-Hodgkin Lymphoma (Burkitt, Large Cell, Lymphoblastic, Anaplastic)*
  • Hodgkin Lymphoma*
  • Neuroblastoma*
  • Brain Tumors*
  • Wilms Tumor*
  • Sarcomas*
  • Others

Non-Malignant Diseases

  • Bone Marrow Failure syndromes*
  • Hemoglobinopathies*
  • Immunodeficiencies (SCID, Wiskott-Aldrich, Hemophagocytic Lymphohistiocytosis (HLH)*
  • Metabolic*
  • Autoimmune Diseases*
  • Myelofibrosis*
  • Others

Bone Marrow Failure Syndromes

  • Bone Marrow Failure syndromes*
  • Amegakaryocytic Thrombocytopenia
  • Aplastic Anemia
  • Congenital Neutropenia (Kostmann syndrome)
  • Diamond Blackfan (Red Cell Aplasia) Anemia
  • Dyskeratosis Congenita
  • Fanconi Anemia
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)
  • Reticular Dysgenesis
  • Shwachman-Diamond Syndrome
  • Thrombocytopenia with Absent Radii (TAR)
  • Others

Rare Genetic and Metabolic Disorders

  • Adrenoleukodystrophy
  • Diseases of IL10 and IL10 Receptor
  • Hurler Syndrome
  • Krabbe Disease
  • Metachromatic Leukodystrophy
  • Niemann Pick Disease
  • Osteopetrosis
  • Others

Unique Features

  • FACT Accredited
  • COG Accredited
  • NMDP Accredited
  • Pediatric Blood and Marrow Transplantation Consortium (PBMTC) member
  • Cellular and Tissue Engineering Laboratory “GMP Quality”
  • Cord Blood Diseases & Regenerative Therapy Program
  • Cord Blood Transplantation Program
  • Unrelated Adult Donor Stem Cell Program
  • Haploidentical Stem Cell Program
  • Extracorporeal Photopheresis
  • On-site leukapheresis for peripheral stem cell collection and bone marrow stem cell harvesting
  • T-cell Depletion and Stem Cell Selection Program
  • High-Risk Leukemia Consortium (Lead Institution)
  • Lymphoma Cell Therapy Consortium (Lead Institution)
  • Sickle Cell Transplantation Consortium (Lead Institution)
  • Ten HEPA Filtered and Positive Pressure Inpatient Rooms
  • Personalized and customized blood, marrow and cellular therapies
  • Multidisciplinary Programs
  • Palliative Care Program
  • Developmental Therapeutics Program
  • Long-Term Survivors Program
  • Adolescent and Young Adult (AYA) Program

Hematotherapy Department

As part of the Westchester Medical Center Cancer Center, the Hematotherapy Department provides outpatient transfusion and infusion services for both adult and pediatric hematology/oncology patients at Westchester Medical Center and Maria Fareri Children's Hospital. We provide personalized, high quality care for a large variety of malignancies including ALL, AML, CML, JMML, NHL, HL, MDS, MM, neuroblastoma, brain tumors, Wilms Tumor, germ cell tumors, sarcomas and more. Patients are treated with transfusion of blood and blood products and administrated chemotherapy and/or immunotherapy. We perform Autologous and Allogeneic Cellular Therapy collections as well as Mononuclear cell collections used to generate cytotoxic t-lymphocytes for the treatment of post transplantation infections. We are approved to treat patients with Acute Lymphoblastic Leukemia and a variety of B-cell lymphomas with chimeric antigen receptor (CAR) T-cells. Therapeutic Plasmapheresis is used to reduce donor specific antibodies. Extracorporeal Photopheresis is used for the treatment of acute and chronic Graft vs. Host Disease and CTCL.

Our Cellular Therapy program is fully accredited by NYDOH, FDA and FACT (Foundation for the Accreditation of Cellular Therapy).

The Outpatient Hematotherapy Department has a total of six ONS/ONCC Chemotherapy/Immunotherapy certified RN staff who are qualified through training and experience in pediatric and adult care as well as apheresis, photopheresis and Cellular Therapy Collection processes. On-site medical supervision is provided by our team of Hematology/Oncology physicians under the direction of the program medical director.

Research and Education Highlights

  • ACGME Accredited Pediatric Hematology, Oncology, and Stem Cell Transplantation Fellowship Program
  • Student, Resident and other Allied Health Professions elective/selectives
  • Tumor Immunology
  • Transplantation Immunology
  • Adoptive Targeted Cellular Therapy
  • Stem Cell Biology, Regenerative, and Hematopoiesis


Westchester Medical Center now offers FDA-approved CAR T-Cell Therapies that use your own immune system to fight certain types of cancer.   

CAR T-cell therapy is a form of immunotherapy that involves using your own immune cells to fight your cancer. The specific immune cells (T-Cells) are isolated from the blood stream and genetically modified to produce new cells called chimeric antigen receptors (CARS) T-cells. Once these new CAR T-cells are reinfused back into the body, they are able to target and attack your cancer cells.

 

 

CAR T-Cell Therapy Products

There are several different types of CAR T-cell therapy products for treatment of the following diseases:

Kymriah® (Novartis): https://kymriah.com

DLCBL: Adult patients with relapsed or refractory (r/r) diffuse large B-cell lymphoma after two or more lines of systemic therapy including diffuse large B-cell lymphoma (DLBCL) not otherwise specified, high grade B-cell lymphoma and DLBCL arising from follicular lymphoma.

B-Cell ALL: Patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.



Tecartus® (Kite): https://www.tecartus.com

MCL: Adult patients with relapsed or refractory Mantle Cell Lymphoma.



Yescarta® (Kite): https://www.yescarta.com

DLCBL: Adult patients with relapsed or refractory (r/r) diffuse large B-cell lymphoma after two or more lines of systemic therapy including diffuse large B-cell lymphoma (DLBCL) not otherwise specified, high grade B-cell lymphoma and DLBCL arising from follicular lymphoma.

Follicular Lymphoma: Adult patients with relapsed or refractory follicular lymphoma (FL) after two or more lines of systemic therapy.


Contact Us

Pediatric Hematology, Oncology and Stem Cell Transplant
Maria Fareri Children’s Hospital
100 Woods Road
Valhalla, NY 10595
914.493.7997

The Westchester Medical Center Hematotherapy Department
19 Bradhurst Avenue
Suite 2200N
Hawthorne, NY 10532

By Car

Train

Maria Fareri Children’s Hospital is served by Metro North's Harlem line via two stations:

  • White Plains - Bus transfer options available
  • Hawthorne - Taxi service available For train fare and schedule information, call 1-800-METRO-INFO or go to METRO NORTH

Bus

There are three bus lines (Westchester Bee Line) you can take to our campus. Please call 914.813.7777 for bus routes and fares.

Campus Map

The Westchester Medical Center campus includes the Maria Fareri Children's Hospital and the Behavioral Health Center.


Mitchell Cairo, MD
Pediatric Hematology-Oncology
Clinical Director of Hematotherapy
Clinical Director of Non-Malignant Stem Cell Transplantation

Aliza Gardenswartz, MD
Assistant Professor of Pediatrics
Director, Sickle Cell Program
Hematological Malignancies Program
Cellular Therapy and Stem Cell Transplantation Program

Nurse Coordinators


Meghan Sturhan, RN, MSN, CPNP-AC, CPHON
Meghan.Sturhan@wmchealth.org
914.594.2162

Isabel Gonzalez, RN, MS, CPNP-PC
Isabel.Gonzalez@wmchealth.org
914.594.2154

Cellular Therapy Program

Amir Steinberg, MD, FACP
Clinical Director for Adult Stem Cell Transplantation

Aliza Gardenswartz, MD
Pediatric Hematological Malignancies Program
Cell Therapy and Stem Cell Transplantation

Cell Therapy Coordinators

Patty Mc Hale, RN (Adult)
Patricia.McHale@wmchealth.org
914.493.2276

Isabel Gonzalez, CPNP (Pediatrics) 
Isabel.Gonzalez@wmchealth.org 
914.594.2162

Megan Campbell, FNP-C (Pediatrics) 
Megan.Campbell@wmchealth.org
914.594.2154

Sandra Fabricatore, CPNP
Sandra.fabricatore@wmchealth.org
Quality Nurse Coordinator